The NY Times reports that scientists have identified a mutation which shuts down the function of the human apoC-III gene. This results in an enhanced ability to quickly break down fat, and it lowers LDL cholesterol and raises HDL...plus, just for the heck of it, keeps arteries plaque-free. Not bad, huh?
On the other hand, I worry about the unintended consequences of shutting down this gene. I'd like to talk to the folks with this mutation before I get all excited about one day choosing to have my own apoC-III knocked out of commission. It might turn out they can't correctly punctuate sentences or appreciate flamenco or crack their knuckles.
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